Technical Specifications
Material Quantity: 1250 kg per batch
Low Temperature of Cold Trap: ≤-50℃
Large Capture Volume: 1500 kg per batch
Ultimate vacuum degree: ≤5 Pa
Total Power: 185 kW
Equipment installation area and height: 240m² x 4.5m
Weight: 4,000 kg
Features of this machine
1. Pre-freezing and drying are completed in situ, with the freeze-drying process automated for easy operation.
2. The layers circulate a medium, with adjustable temperature; temperature difference ≤ 1°C, providing more even cooling and heating effects.
Touchscreen operation, PLC control system, real-time monitoring of equipment operation.
4. Connectable to computers for remote control and storage of freeze-drying curves.
5. Integrated design for easy transportation and installation, saving space.
6. Features include CIP in-situ cleaning, SIP in-situ sterilization, hydraulic plug-in system, and more.
Equipment Application Fields
Pharmaceutical Industry: Cryogenic drying technology can be used for the dehydration and preservation of various Chinese and Western medicines, such as powders, pastes, vaccines, enzymes, antibiotics, hormones, etc.
2. Food Industry: Vacuum freeze-drying technology is primarily used in the food industry for drying coffee, leafy vegetables, juices, strawberries, whole shrimp, meats, specialty vegetables, etc., which can preserve the color, aroma, flavor, shape, and nutritional value of the food unchanged. It facilitates long-term storage and transportation and is highly suitable for the production of convenient and nutritious food products.
3 Nutritional Health Products: The vacuum freeze-drying technique is also used for drying royal jelly, pearl powder, ginseng, fish meal, ant powder, snake powder, and more. It can preserve their nutritional and active components for long periods.
Ensure the naturalness of nutritional supplements.
4. Biological Research: Utilizing vacuum freeze-drying technology, bacteria, arteries, bones, skin, corneas, nerve tissues, and various organs can be preserved for long periods. Upon use, water can be supplied to regenerate them, maintaining their integrity.
Its biochemical and physical characteristics.
5. Other applications, such as in the production of aerospace thermal insulation ceramics, wood and silk materials in archaeology, product preservation, specimen making, and special material preparation, yield unique effects.
Principle of Freeze-Drying
Drying is one method of preserving substances from spoilage and deterioration. There are many ways to dry, such as sun drying, boiling dry, air drying, spray drying, and vacuum drying, etc. However, these drying methods are all based onPerform at temperatures of 0℃ or higher. The dried product generally has reduced volume, hardened texture, some oxidation of substances, and most volatile components are lost. Heat-sensitive substances, such as proteins, may denature. Microorganisms lose biological activity, and the dried material is not easily soluble in water. Therefore, there are significant differences in properties between the dried product and the original, unlike the above drying methods which are not cryodrying. In cryodrying, the product is dried at temperatures below 0℃—specifically, while the product is frozen—until the later stages, when the product is raised to temperatures above 0℃ to further reduce residual moisture content, but usually not exceeding 50℃. Cryodrying involves pre-freezing a substance with a high water content into a solid, then under vacuum, allowing water vapor to sublime directly, leaving the substance itself in the ice framework from the freezing stage. Consequently, the dried product is loose, porous, and maintains its volume. To decrease the product's temperature and slow the sublimation rate, heating is necessary to increase the sublimation speed and shorten the drying time. The entire drying process is conducted at lower temperatures.
The Advantages of Freeze-Drying
1. Freeze-drying is conducted at low temperatures, making it particularly suitable for many thermosensitive substances, such as proteins and microorganisms, which do not denature or lose their biological activity. As a result, it is widely used in pharmaceutical applications.
2. During low-temperature dry roasting, there is minimal loss of volatile components in the material, making it suitable for drying certain chemical products, pharmaceuticals, and food.
3. During the freeze-drying process, microbial growth and enzyme activity are halted, thus preserving the original characteristics.
4. Due to drying in a frozen state, the volume remains almost unchanged, preserving the original structure and avoiding concentration.
5. The dried substance is loose and porous, resembling a sponge. Upon addition of water, it dissolves rapidly and completely, restoring to its original properties almost instantly.
6. Due to the drying process taking place under vacuum, with reduced oxygen levels, some easily oxidizable substances are protected.
7. Drying can remove over 95% of the moisture, ensuring the product can be stored long-term without spoilage after drying.
Therefore, freeze-drying is currently widely used in the pharmaceutical industry, food industry, scientific research, and other departments.
