Technical Specifications
Material Quantity: 1350 kg per batch
Low Temperature of Cold Trap: ≤-50℃
Large catch water capacity: 1800kg/batch
Ultimate vacuum degree: ≤5 Pa
Total Power: 237 kW
Equipment installation area and height: 240m² x 4.5m
Weight: 4000 kg
Features of this unit
Flash-freezing and drying are completed in situ, with the freeze-drying process automated and operation simplified.
2. The board layer circulates a medium with adjustable temperature, with a temperature difference of ≤1°C, ensuring more even cooling and heating effects.
Touchscreen operation, PLC control system, real-time monitoring of equipment operation.
4. Connectable to computers for remote control and storage of lyophilization curves.
5. Integrated design for easy transportation and installation, saving space.
6. Features include CIP in-place cleaning, SIP in-place sterilization, hydraulic plug-in system, and more.
Equipment Application Fields
Pharmaceutical Industry: The freeze-drying technology can be utilized for the dehydration and preservation of dry powders, pastes, vaccines, enzymes, antibiotics, hormones, and other Chinese and Western medicines.
2. Food Industry: Vacuum freeze-drying technology is primarily used in the food industry for drying coffee, leafy vegetables, juices, strawberries, whole shrimp, meats, specialty vegetables, etc. It preserves the color, aroma, flavor, shape, and nutritional content of the food, making it convenient for long-term storage and transportation. It is particularly suitable for the production of convenient and nutritious food products.
3 Nutritional Health: Direct vacuum freeze-drying technology can also be used for drying royal jelly, pearl powder, ginseng, fish meal, black ant powder, snake powder, etc., which can preserve their nutritional and active ingredients for a long time.
Ensure the naturalness of nutritional supplements.
4. Biomedical Research: Utilizing vacuum freeze-drying technology, bacteria, arteries, bones, skin, corneas, nerve tissues, and various organs can be preserved for long-term storage. Upon use, water can be supplied to regenerate them, maintaining their integrity.
Its biochemical and physical properties.
5. Other applications, such as in the production of aerospace thermal insulation ceramics, wood and silk conservation in archaeology, product preservation, specimen creation, and special material preparation, yield unique effects.
Principle of Freeze-Drying
Drying is one method of preserving substances from spoilage and deterioration. There are numerous drying techniques, such as sun drying, boiling dry, air drying, spray drying, and vacuum drying, among others. However, these drying methods are all based onPerform at temperatures of 0℃ or higher. The dried product is generally reduced in volume, hardened in texture, with some substances oxidized, and most volatile components lost. Some thermosensitive substances, like proteins, may denature. Microorganisms lose biological activity, and the dried substance is not easily soluble in water. Therefore, the dried product differs greatly in properties from the original, and the freeze-drying process differs from the above drying methods. The product is dried primarily at temperatures below 0℃, i.e., while in a frozen state, until later stages when the product is raised to temperatures above 0℃ to further reduce residual moisture content, but usually not exceeding 50℃. Freeze-drying involves pre-freezing a substance containing a large amount of water into a solid, then, under vacuum, allowing water vapor to sublime directly, leaving the substance in the ice matrix from the freezing stage. Thus, the dried product is fluffy and porous with no change in volume. To decrease the product's temperature and slow down the sublimation rate, it is necessary to apply appropriate heating. The entire drying process is carried out at lower temperatures.
The advantages of freeze-drying
1. Freeze-drying is conducted at low temperatures, making it particularly suitable for many thermosensitive materials, such as proteins and microorganisms, which do not denature or lose their biological activity. Therefore, it is widely used in pharmaceutical applications.
2. During low-temperature dry roasting, there is minimal loss of volatile components in the material, making it suitable for drying certain chemical products, pharmaceuticals, and food.
3. During the freeze-drying process, microbial growth and enzyme activity are halted, thus preserving the original characteristics.
4. Due to drying in a frozen state, the volume remains almost unchanged, preserving the original structure and preventing concentration.
5. The dried substance is loose and porous, resembling a sponge, dissolving quickly and completely when water is added, almost immediately reverting to its original properties.
6. Due to the drying process being carried out under vacuum, with reduced oxygen levels, some easily oxidizable substances are protected.
7. Drying removes over 95% of moisture, allowing the product to be preserved for a long time after drying without deterioration.
Therefore, freeze-drying is currently widely used in the pharmaceutical industry, food industry, scientific research, and other sectors.
