Technical Specifications
Material Quantity: 2000 kg per batch
Low temperature of cold trap: ≤-50℃
Large Water Catching Capacity: 2400kg/batch
Ultimate vacuum degree: ≤5 Pa
Total Power: 350 kW
Equipment installation area and height: 380m² x 4.5m
Weight: 40,000 kg
Features of the unit
1. Pre-freezing and drying are completed in situ, with the freeze-drying process automated for easy operation.
2. The board layer circulates a medium, allowing for adjustable temperature with a temperature difference of ≤1°C, ensuring more even cooling and heating effects.
Touchscreen operation, PLC control system, real-time monitoring of equipment operation.
4. Connectable to computers for remote control and storage of lyophilization curves.
5. Integrated design for easy transportation and installation, saving space.
6. Features include CIP in-place cleaning, SIP in-place sterilization, hydraulic plug-in system, and more.
Equipment Application Fields
Pharmaceutical Industry: Cryogenic drying technology can be used for the dehydration and preservation of various Chinese and Western medicines such as dry extracts, pastes, vaccines, enzymes, antibiotics, and hormones.
2. Food Industry: Vacuum freeze-drying technology is primarily used in the food industry for drying coffee, leafy vegetables, fruit juices, strawberries, whole shrimp, meats, specialty vegetables, etc. It preserves the color, aroma, flavor, shape, and nutritional content of the food, making it convenient for long-term storage and transportation. It is particularly suitable for the production of convenient and nutritious food products.
Nutritional Health: The vacuum freeze-drying technique can also be used to dry royal jelly, pearl powder, ginseng, fish meal, ant powder, snake powder, and more. It preserves their nutritional and active components for long-term storage.
Guarantee the naturalness of nutritional supplements.
4. Bioresearch: Utilizing vacuum freeze-drying technology, bacteria, arteries, bones, skin, corneas, nerve tissues, and various organs can be preserved for long periods. Upon use, water can be supplied to regenerate them, maintaining their integrity.
Its biochemical and physical characteristics.
5. Other applications such as in the production of aerospace thermal insulation ceramics, wood and silk artifacts in archaeology, preservation of products, specimen creation, and preparation of special materials yield unique effects.
Principle of Freeze-Drying
Drying is one method of preserving substances from spoilage and deterioration. There are numerous ways to dry, such as sun-drying, boiling dry, air-drying, spray drying, and vacuum drying, among others. However, these drying methods are all based onConduct at temperatures of 0℃ or higher. The dried product typically shrinks in volume, hardens in texture, and some substances may oxidize. Most volatile components are lost, and heat-sensitive substances like proteins can denature. Microorganisms lose their biological activity, and the dried material is not easily soluble in water. Therefore, the dried product differs significantly in properties from the original, unlike freeze-drying, which does not involve drying above 0℃. Instead, the process occurs while the product is frozen, and it is only raised above 0℃ towards the end to further reduce residual moisture content, usually not exceeding 50℃. Freeze-drying involves pre-freezing a product with a high water content, then allowing water vapor to sublime directly under vacuum, leaving the substance trapped in the ice framework. This results in a dried product that is fluffy, porous, and maintains its volume. To slow down the sublimation rate and speed up the drying time, the product must be slightly heated. The entire drying process takes place at lower temperatures.
Advantages of Freeze-Drying
1. Freeze-drying is conducted at low temperatures, making it particularly suitable for many thermosensitive substances, such as proteins and microorganisms, which do not denature or lose their biological activity. Therefore, it is widely used in pharmaceutical applications.
2. During low-temperature drying, the loss of volatile components in the substance is minimal, making it suitable for drying some chemical products, pharmaceuticals, and food.
3. During the freeze-drying process, the growth of microorganisms and the action of enzymes are halted, thus preserving the original properties.
4. Due to drying in a frozen state, the volume remains almost unchanged, preserving the original structure and preventing any concentration.
5. The dried material is loose and porous, resembling a sponge. Upon addition of water, it dissolves quickly and completely, almost immediately regaining its original properties.
6. Due to the drying process being carried out under vacuum, with less oxygen present, some substances prone to oxidation are protected.
7. Drying can remove over 95% of moisture, ensuring the product can be stored long-term without deterioration after drying.
Thus, freeze-drying is currently widely applied in the pharmaceutical industry, food industry, scientific research, and other departments.
