Technical Specifications
Material intake quantity10kg per batch
Cold Trap Low Temperature:≤-60℃
High Water Flow Capacity15 kg per batch
Ultimate vacuum level:<1Pa
Total Power:12kw
Equipment dimensions:2214*1000*2030mm
Weight:1500kg
Key Features of This Unit
1. Pre-freezing and drying are completed in situ, with the freeze-drying process automated and operation simplified.
2. The layers circulate a medium, allowing for adjustable temperature with a temperature difference of ≤1°C, ensuring more even cooling and heating effects.
3. Touchscreen operation, PLC control system, real-time monitoring of equipment operation.
4. Connectable to a computer, allows for remote control and stores lyophilization curves.
5. Integrated design for easy transportation and installation, space-saving.
6. Features include in-situ CIP cleaning, SIP disinfection, and hydraulic plug system connectivity.
Equipment Application Fields
Pharmaceutical Industry: The freeze-drying technique can be applied for the dehydration and preservation of various traditional and Western medicines such as dry extracts, plasma, vaccines, enzymes, antibiotics, hormones, etc.
2. Food Industry: Vacuum freeze-drying technology is primarily used in the food industry for drying coffee, leafy vegetables, juices, strawberries, whole shrimp, meats, specialty vegetables, etc. It preserves the color, aroma, flavor, shape, and nutritional content of the food, making it convenient for long-term storage and transportation. It is highly suitable for the production of convenient and nutritious food products.
3 Nutritional Health Products: The vacuum freezing drying technology is also suitable for drying royal jelly, pearl powder, ginseng, fish meal, black ant powder, snake powder, etc., ensuring the long-term preservation of their nutritional and active ingredients while maintaining the natural essence of the nutritional products.
4. Bioresearch: The vacuum freeze-drying technique can preserve bacteria, arteries, bones, skin, corneas, nerve tissues, and various organs for long-term storage. Upon use, water can be supplied to regenerate them, maintaining their biochemical and physical properties.
5. Other applications, such as in the production of aerospace thermal insulation ceramics, wood and silk artifacts in archaeology, preservation of products, specimen making, and preparation of special materials, yield unique effects.
The Principle of Freeze-Drying
Drying is one method of preserving substances from decay and spoilage. There are many ways to achieve dryness, such as sun-drying, boiling dry, air-drying, spray drying, and vacuum drying, among others. However, these drying methods are all based onPerform at temperatures above 0℃ or higher. The dried product is generally reduced in volume, harder in texture, with some substances oxidized, and most volatile components lost. Heat-sensitive substances, such as proteins, may denature. Microorganisms lose their biological activity, and the dried material is not easily soluble in water. Consequently, there are significant differences in properties between the dried product and the original, unlike the above dry-roasting methods, where the product is dried at temperatures below 0℃—specifically, in the frozen state—until the later stages when the product is raised to temperatures above 0℃ to further reduce residual moisture content, but usually not exceeding 50℃. Freeze-drying involves pre-freezing the moisture-rich substance and then, under vacuum conditions, allowing water vapor to sublime directly, leaving the substance itself in the ice framework formed during freezing. Thus, the dried product is loose and porous with no change in volume. To decrease the product's temperature and slow the sublimation rate, it is necessary to apply appropriate heating. The entire drying process is conducted at lower temperatures.
Advantages of Freeze-Drying
1. Freeze-drying is conducted at low temperatures, making it particularly suitable for many thermosensitive substances, such as proteins and microorganisms, which do not denature or lose their biological activity. As a result, it is widely used in the pharmaceutical industry.
2. During low-temperature dry roasting, there is minimal loss of volatile components in the material, making it suitable for drying certain chemical products, pharmaceuticals, and food.
3. During the freeze-drying process, the growth of microorganisms and the action of enzymes are halted, thus preserving the original properties.
4. Due to drying in a frozen state, the volume remains almost unchanged, preserving the original structure and preventing any concentration.
5. The dried substance is loose and porous, resembling a sponge, and dissolves quickly and completely when water is added, almost immediately reverting to its original properties.
6. Due to the drying process taking place under vacuum with limited oxygen, some materials that are prone to oxidation are protected.
7. Drying can remove over 95% of moisture, ensuring the product can be stored for a long time after drying without deterioration.
Therefore, freeze-drying is currently widely applied in the pharmaceutical industry, food industry, scientific research, and other sectors.
