NFSI is a novel, stable, and mild fluorinating reagent that can introduce fluorine atoms into the ortho position of carbonyl groups in organic molecules. It is suitable for single fluorination reactions of electron-rich aromatic compounds, enol siles, and enol lithium salts. Current research hotspots include the Nazarov cyclization reaction forming a five-membered ring under iron or cobalt catalysis, and asymmetric catalysis for enantioselective α-fluorination.

Basic Information:

N-Fluorinated biphenyl sulfonamide

Synonyms: N-Fluoro-benzene磺酰亚胺, N-Fluorodiphenylsulfonyl imide, N-Fluorodibenzene sulfonamide

N-Fluorobenzene sulfonimide

NFSI

CAS Registry Number: 133745-75-2

Molecular Formula: C₁₂H₁₀FNO₄S₂

Molecular Weight: 315.34 g/mol

Product Images

Physical Properties

Melting Point: 114-118℃

Relative Density: 1.527 g/cm³³

Product Specifications

Purity: HPLC ≥98.0%

Packaging: 25kg cardboard drum or as per customer's requirement

Appearance: White Powder Crystals