详情描述



 

Guanidine hydrochloridePHMB- 95% Solid Powder

Product Advantages

◆  Sorry, there is no Chinese content provided to translate. Spectrum antibacterial, with significant antibacterial effect; effective against Gram-positive bacteria, Gram-negative bacteria, and fungi (multiple types)

Ringworm, mold, and yeast all possess killing capabilities.

◆  Effective against pathogenic microorganisms (such as E. coli) and actively resistant to antibiotic-resistant bacteria (such as)MRSA)

◆  Actively combats bacteria that cause odors, hence offering antibacterial and deodorizing properties.

Non-toxic, non-irritating to skin, mucous membranes, and eyes, and non-sensitizing.

Non-specific physical sterilizationNo content provided.Easily generates bacterial resistance, exhibits corrosion inhibition, and provides long-lasting bactericidal action.

Colorless, odorless,No content provided.Volatile,No content provided.Contains heavy metals, halogens, phenols, and aldehydes; harmful to all surfaces

Corrosion-free processing.

◆  Maintain activity in organic substances, with high activity in both hard and soft water. Treatment solutions

Reusable multiple times.

No content provided.Leave streak marks on the surface, easily washable with water, low foam, low surface tension.

◆  Easily dilutes in cold and hot water; the solution is non-flammable and easy to handle.

◆  ZeroVOC-free/No formaldehyde emissions.

Good heat and storage stability.

No effect on the original physical and mechanical properties, color, and dyeing performance of fibers or fabrics.

◆  Wide pH range applicability, stable and effective between 1-11.

◆  For cotton, viscose fibers, and blended fabrics (cellulose content >)30% antibacterial finishingToughOver 50 washesIts safety is certified by the United StatesFDA and EPA approved.

Physical and Chemical Properties

Item       Objective

Guanidine hydrochloride (polyhexamethylene)PHMB

CAS Number

32289-58-0(US)/27083-27-8(EU)

Molecular Formula and Molecular Weight

C8H17N5)n.xHCIn=12-16

Chemical Properties

Cationic polymer

Appearance:

Off-white to light yellow flowable powder

Solids Content:

.95% (w/w)

1% solution pH-Value (25°C)

 4.0-7.0

Flash Point:

100℃

 

 

 

Storage Stability

Store stably under normal conditions.PHMB solid powder is hygroscopic.No content provided for translation.Use requires maintaining Good sealing of the container to prevent moisture intrusion. Preserve Store in original container.PHMB solid has excellent heat resistance (no significant thermal degradation occurs at 235°C).N/AVolatile.

Odor

No strong odor

 

FoamSurface Tension

Low-foaming aqueous solution, less foam than quaternary ammonium compounds

 PHMB is not a surfactant.

Solubility

EasyDissolves in waterCan also be used in combination with disinfectant additives.

Absorbance 0.2%/1cm(by 237nm):

.400

Absorbance Ratio237nm/222nm)

1.2-1.6

Density

1.04g/ml

Decomposition Temperature:

≥400℃

Boiling Point

102

Corrosiveness:

Corrosion-free

Compatibility

Please refer to Table 2 in detail.PHMB Compatibility Warnings

 

 

Antibacterial Principle

PHMBGuanidine possesses high reactivity, enabling polymers to become positively charged, which easily attracts negatively charged bacteria and viruses. This吸附 inhibits their reproductive capabilities and splits, rendering them sterile. Additionally, the film formed by the polymer blocks the respiratory pathways of microorganisms, causing them to asphyxiate and die rapidly.

PHMBAnother active ingredient, hydrochloric acid, enhances the antibacterial effectiveness.

 

Toxicity test

Toxicological tests indicatePHMBAcute oral toxicity test with mice showed no adverse reactions or deaths in the animals, and the same applies to both male and female mice.LD50>5000 mg/kgWeight, according to the acute toxicity classification standards, falls into the practically non-toxic category.

One-time skin irritation test for domestic rabbits: Single contact with rabbit skinPHMBLater, the stimulation points value0Non-irritating.

Rabbit Eye Irritation Test: The score of the rabbit's ocular mucosal (cornea, iris, conjunctiva) irritation response is0Non-irritating.

Guinea Pig Skin Sensitization Test After24H,48HGuinea pig skin test areas showed no significant erythema or edema, with a sensitization rate of0This product is categorized as a mild allergen.

Similarly,PHMBCurrently considered a safe and non-toxic antibacterial disinfectant.

Application FieldSuggested addition quantity             UtilizeProBioTMP100 Concentration (W/W) %

Solid Surface Disinfection                        0.02-0.1%

Yiyuan, Food Processing Plant                    0.002-0.02%

Slaughterhouse, poultry farm, water treatment equipment          0.002-0.02%

Air Conditioners, Fermentation Equipment                      0.06-0.1%

Dairy farm, brewery                      0.08-0.15%

Canned Goods Factory                              0.001-0.002%

    Antibacterial materials :By joiningPHMB solid for making antimicrobial materials, such as PHMB antimicrobial masterbatch, antimicrobial silicone

Gum, AntimicrobialPP, antibacterial PE, and antibacterial fibers, etc.

 

 

PHMB Contraindications

Non-ionic, anionic, and amphoteric surfactants are fully compatible, such as polyoxyethylene fatty alcohols EtherAEO, betaine, ammonium oxide, EO/PO block copolymers, etc.

PHMB has cationic properties. When anionic compounds such as soap are present, they form insoluble salts, leading to a decrease in activity. In addition, it is not compatible with phosphates, strong alkalis, and strong oxidizing agents.

Its compatibility is also limited.

Completely compatible without chelating agents.EDTA (Ethylene diamine tetraacetic acid), NTA (Nitrilotriacetic acid)

Non-polar solvents fully miscible, such as ethanol, diethylene glycol, and diethylene glycol ether.

Incompatible with inorganic acids and many organic acids.HCI, H3PO4, Glycolic Acid

Not fully compatible with cellulose thickening agents.HPC,HEC,HPMC;

Non-pigmented is compatible over a wide range, such as with nitrogenous and sulfonate types.

China's Regulatory Information

PHMBRegistered with the National Environmental Protection Agency Chemicals Registration Center---Listed in the "China Existing Chemical Substances Catalogue"CAS-No.27083-27-8

PHMBEnlisted in the new national standard 《GB-26367-2010 - Guanide Disinfectant Hygiene Standard---Suited for surgical hand antisepsis, hygienic hand antisepsis, preoperative and clinical mucous membrane skin cleansing and disinfection, as well as surface disinfection of objects.

PHMBListed in China's Ministry of Health's "HZP Sanitation Standard"07Version

PHMBListedFood Disinfectant1. Ingredient List (2009 Edition)