The ventilation system is one of the systems with a wide impact on the design and construction of the entire purification workshop. The improvement of the purification engineering ventilation system directly affects the workshop environment, the health of laboratory personnel, and the operation and maintenance of experimental equipment. Issues such as excessive negative pressure in the purification workshop, gas leaks from fume hoods, and workshop noise have always been challenges faced by purification workshop staff. These issues have caused significant physical and mental harm to the management and logistics personnel surrounding the purification workshop. A scientifically and reasonably designed ventilation system requires good ventilation, low noise, simple operation, energy-saving, and even maintaining comfortable indoor pressure difference and humidity levels.