When selecting biological safety cabinets, various factors must be considered. Generally, Class II biological safety cabinets can meet basic working needs. For experiments with samples that do not contain toxic, radioactive, or volatile irritant solvents, A1/A2 (formerly B3) type cabinets are usually sufficient. For hospital system procurement, given the complexity of viruses and bacteria types and the variability of experimental conditions, it is recommended to use B2 full-evacuation biological safety cabinets. The primary criterion for evaluating the quality of a biological safety cabinet is the protection it offers to the operator, with its core technologies including filter membranes (material, retention efficiency, lifespan, etc.), air pathway design (balance on the front operation surface, sedimentation air velocity and uniformity, intake air velocity, vertical air sedimentation pattern, etc.), alarm settings (low air velocity alarms, front window error position alarms, UV interlock devices, etc.), and negative pressure protection (side wall, back, and top negative pressure, etc.).
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