45S5 Bioactive Glass Powder is an inorganic non-metallic material with good bioactivity. The following are some of its physical and chemical parameters and characteristics:
Physical Parameters
Composition: Typically, the chemical formula is Na2O-CaO-SiO2-P2O5, with typical contents of 45% SiO2, 24.5% Na2O, 24.5% CaO, and 6% P2O5.
Appearance: Typically in a white powdered form, particle size can vary depending on the preparation method and application requirements, generally ranging from micrometers to sub-micrometers.
Density: Approximately 2.7-2.8 g/cm^3.
Specific Surface Area: Large, typically around 10-30 m^2/g, high specific surface area facilitates rapid chemical reactions with substances within biological organisms.
Chemical Parameters
Solubility: Possesses a certain solubility in physiological environments, gradually releasing Na+, Ca^2+, Si(OH)4, and PO4^3- ions. These ions play a crucial role in biological mineralization and the regulation of cellular behavior.
pH Value: The pH of its suspension typically ranges between 7-8, close to the human physiological pH, and exhibits good biocompatibility.
Unique Traits
Bioactivity: The 45S5 bioactive glass powder boasts excellent bioactivity, capable of forming tight chemical bonds with human tissue in a short period. After implantation, a layer of hydroxyapatite (HCA) forms on the surface, resembling the inorganic components of human bone, which promotes the adhesion, proliferation, and differentiation of osteoblasts, thereby guiding the growth of new bone tissue.
Biodegradability: It can be gradually broken down and absorbed within biological organisms, and its degradation products can participate in the metabolic processes of the human body, leaving no long-term foreign matter residues.
Osteoconduction: Provides a three-dimensional scaffold structure for the growth of bone tissue, guiding the bone tissue to grow along its surface and internal pores, promoting the repair and reconstruction of bone defects.
Its released ions can disrupt the cell membrane structure of bacteria or interfere with the metabolic process of bacteria.
