Laboratory-grade ultra-fine mill utilizes the combined action of high-speed impact and shearing forces, significantly reducing the time required for grinding and enhancing efficiency. It can completely grind without any drug residue. It can achieve particle sizes as small as 10 μm or even smaller, which can notably increase the solubility and absorption of oral preparations within the body, potentially achieving the efficacy of the original formula with a lower dose. Powder formulations obtained through ultra-fine milling technology better meet the requirements of traditional Chinese medicine prescriptions. The introduction of ultra-fine milling technology in external use powders can increase drug dispersibility, facilitate application and adhesion, enhance the penetration of active ingredients into the skin, and reduce skin irritation. In solid dosage forms such as syrups, capsules, tablets, and films, incorporating ultra-fine milling technology at certain stages of the manufacturing process may improve solubility, disintegration, absorption rate, adhesion, and bioavailability. Products made by ultra-fine powder technology have rapid onset, high bioavailability, can enhance efficacy, reduce adverse reactions, decrease the dosage, and save on medicinal materials. During the ultra-fine milling process, overheating can be controlled, and the process can even be conducted at low temperatures, ensuring rapid grinding. This is beneficial for preserving bioactive components and various nutrients that are sensitive to heat, thereby enhancing the efficacy of the medication.
Herb pulverization is a crucial step in the process of traditional Chinese medicine production. The ease of herb pulverization primarily depends on the structure and properties of the substance, but it is also closely related to the magnitude of external force. The external forces exerted by various pulverizing machinery on the material to be pulverized include the following types: cutting, squeezing, grinding, impacting, splitting, tearing, and filing, etc. To achieve the desired pulverization effect, it is necessary to select different types of pulverizing machinery that act with external forces based on the properties of the drug. When choosing a pulverizing equipment, pay attention to the following points:
1. Equipment processing capacity and production matching.
2. Does the equipment material meet the requirements for pharmaceutical production?
3. High control over crushing and strict environmental hygiene requirements are necessary, in compliance with GMP.
4. The temperature control inside the granulator is strictly maintained, particularly for thermosensitive herbs and flammable, explosive materials.
5. Special material crushing requirements for drugs with high toughness, adhesiveness, high oil content, and high sugar content.
6. Suitable site conditions.
7. Vibration and noise control meets environmental protection requirements.
8. Select a crusher based on the nature of the material to be crushed, the required particle size of the product, and the crushing form used by the crushing equipment.
The Jun Cheng ultra-fine mill is widely recognized by customers, superior to products from other brands, mainly due to:
1. Product Process:
The Jun Cheng Cell Disruption Machine is a vibratory ultra-fine pulverizer that utilizes high-frequency vibration of grinding media to produce shock-shear, friction, and compression effects for particle crushing. The finished product has an average particle size of less than 2-3 micrometers, with high crushing efficiency and strong crushing power. It employs a fully enclosed multi-grinding, non-screening technology to preserve the efficacy components, effectively preventing the segregation and loss of efficacy components, as well as environmental pollution due to dust overflow. Particularly important is the application of ultra-low temperature crushing technology, which is especially suitable for fibrous, thermosensitive, and heat-sensitive traditional Chinese medicinal materials. It is beneficial for retaining the bioactive components of traditional Chinese medicinal materials.
2. Product upgrade and modification:
The small and medium-sized Juncheng ultra-fine pulverizers are equipped with foot-pedal lifting devices for easy loading and unloading. The large ultra-fine pulverizer uses an air-lifting mechanism, which is simple and easy to operate. Both medium and large ultra-fine pulverizers feature a full-water jacket cooling system with cooling water circuits on the inside, outside, and sides for superior cooling effects. The small and medium-sized ultra-fine pulverizers previously used belt-driven flexible connections, but the Juncheng model has been upgraded to a shaft-driven connection, maintaining the amplitude and ensuring stable vibration frequency for uniform pulverizing. As customer requirements for products increase, we can customize ultra-fine pulverizers with different materials, models, and specifications to meet customer needs. Developing advanced pulverizing equipment, innovating pharmaceutical pulverizing technology, and enhancing the digital quality control level of traditional Chinese medicine products are the continuous pursuits of Jinan Juncheng Machinery and Equipment Co., Ltd.
3. Product Processing:
A wide range of product models is available, allowing for customization of ultra-fine pulverizers with different models, specifications, and materials to meet customer demands, offering greater flexibility in selection.
4. Product Pricing:
Juncheng Ultra-Fine Pulverizing Equipment is factory direct, specializing in the professional design, research and development, and production of low-temperature ultra-fine pulverizers and low-temperature cell wall breaking machines. The company integrates research and development, manufacturing, sales, and service, with dedicated teams for research and development, sales, installation and debugging, technical training, and parts supply. We offer professional technical guidance, reliable parts supply, and after-sales service. As a manufacturer, we save consumers the cost of intermediaries, offering competitive prices.
5. Crushing and processing technology implementation:
The company has been dedicated to the research and production of ultra-fine grinding machines from an early stage, having conducted practical粉碎 techniques on thousands of materials. We are adept at mastering the grinding time, temperature, and methods for various materials, offering process support to our clients.
Jinan Juncheng superfine mill's crushing features:
1. High crushing power and efficiency: With a high medium filling rate, it utilizes high-frequency vibration, impact shearing, friction, and compression to crush particles, resulting in a finished product with an average particle size below 2-3 micrometers. Reduces production cycle and improves work efficiency.
2. Uniform Fineness of Pulverization: The distribution of force on the raw materials by the vibration mill is quite even, preventing excessive fineness. The obtained ultra-fine powder has a uniform particle size distribution and a neat appearance. At the same time, it greatly increases the specific surface area of the fine powder, thereby enhancing its adsorption and solubility properties.
3. Low-Temperature Grinding: Equipped with a cooling closed-loop system and refrigeration system, the mill grinds at low temperatures, offering fast processing speed and instant completion. The grinding process does not overheat, which is beneficial for preserving the biological active components of the powder, facilitating the production of high-quality products as required.
4. Full-enclosed Crushing: The equipment operates in a fully enclosed system, where ultra-fine crushing of materials is conducted under sealed and purified conditions, ensuring high purity and preventing component segregation and loss. Effectively prevents dust issues generated during the production process of the crusher, efficiently utilizes resources, and avoids waste.
5. Non-classified Crushing: Utilizes a single-pass, non-classified crushing method where materials are instantly shattered by external impact, achieving a powdered form in one go. The advanced technology and process achieve precise blending (dispersion and emulsification) during crushing, making it simple and easy to operate. Micro-powders are prepared using a physical method, without chemical reactions, thus preserving the original chemical properties of the material.
6. GMP Design: Technical standards, implemented in accordance with food and pharmaceutical production standards, equipment quality meets GMP technical requirements.
7. Energy-saving and Environmental Protection: Ultra-fine powder maximizes the use of raw materials, efficiently utilizes resources, and reduces costs. The crushing machine is equipped with a composite noise-insulating hood, reducing noise pollution. The fully enclosed crushing process ensures no dust and no pollution, meeting environmental protection requirements.
8. Smart Operating System: Equipped with an intelligent operating system, smart electrical components effectively link the粉碎mechanical units, enhancing production efficiency while tapping into the inherent potential of the machinery itself.
