Cell Wall Breaking Mill for Powder Production

The Jun Cheng Cell Disruption Mill is powerful, utilizing external vibration mechanical force to transform mechanical energy into free energy, breaking the intermolecular cohesive forces of substances to achieve the purpose of crushing. It can crush various Chinese herbal medicines to ultra-fine and nanometer levels. The resulting fine powder has a large surface area and porosity, even quality, excellent solubility, strong adsorption, fluidity, fast reaction rate, and high solubility. This mill can achieve cell disruption for the majority of traditional Chinese medicinal materials. It can increase the particle size of raw materials from the traditional 100-150 mesh to over 1000 mesh, significantly improving the cell disruption rate for general herbs. This new technology is suitable for various herbs with different textures, directly exposing their active ingredients, leading to faster and more complete drug efficacy. The crushed Chinese herbs can then be processed into various tablets, capsules, and granules using tablet presses, capsule filling machines, filling machines, and granulating machines, ensuring better pharmacological properties and improved patient compliance.

The Juncheng Cell Disruption Mill is a vibration mill that distributes force on the raw materials quite evenly. The resulting ultra-fine powder has a uniform particle size distribution, neat appearance, and significantly increases the specific surface area of the micronized powder, thereby enhancing its adsorption and solubility properties as well.

The Juncheng Grinding Mill features a cooling closed-loop system within the grinding chamber, equipped with a refrigeration system. It operates at low temperatures for efficient crushing, completing the process quickly without overheating. This method preserves the biological active components of the powder, conducive to producing high-quality products. Utilizing ultra-low temperature cell wall-breaking technology, the nutritional components are enhanced several times without being damaged, with a high cell wall-breaking rate. After cell wall-breaking, particles form stable aggregates, each containing an equal proportion of herbal ingredients, facilitating absorption and utilization by the human body. After ultra-fine processing, the effective components within the cells are fully released, enhancing the lipid solubility of the herbs. The drugs can better disperse and dissolve in gastrointestinal fluids, with increased contact area with the gastrointestinal mucosa, making it easier for the gastrointestinal tract to absorb them, significantly improving the bioavailability and the absorption of active components several times over.

The Juncheng Milling Machine ensures uniform distribution of active ingredients in traditional Chinese medicine, achieving precise mixing. It can perform micro-complexation and coating of two or more materials. It is also suitable for liquid-grain and grain-grain interfaces; it enhances emulsification, prevents separation of materials in a short time, and achieves strong homogenization with high solid content. It improves the compression and granulation properties of traditional Chinese medicine, offering good taste and ease of use.
The Jun Cheng Cell Disruption Mill can achieve cell wall-breaking level pulverization of traditional Chinese medicine, as the contents of the cells can directly contact the solvent, allowing all active ingredients to enter the solvent and be absorbed by the human body. Due to the small particle size of the cell-level micro-powder, the action of beneficial bacteria is faster and stronger, resulting in a significant increase in the quantity and concentration of the products generated by the bacteria, which is beneficial for absorption and enhances absorption rate. The small particles of traditional Chinese medicine fragments strengthen their adhesion to the intestinal wall, extending the stay time of the particles in the intestines, which is favorable for absorption. Solid dosage forms are often composed of various materials. The application of Jun Cheng ultra-fine pulverization technology in granules, capsules, tablets, and film preparations improves solubility, disintegration, absorption rate, adhesion, and bioavailability.
For manufacturers, this simplifies the extraction process, shortens the extraction time, thereby achieving the dual goals of reducing the production cycle and conserving energy.