Technical Specifications
Material Quantity: 150kg per batch
Low Temperature of Cold Trap: ≤-60℃
Large catch water capacity: 225 kg/batch
Ultimate vacuum: ≤1 Pa
Total Power: 64 kW
Equipment installation area and height: 40m x 2.6m
Weight: 8,500 kg
Key Features of the Unit
1. Pre-freezing and drying are completed in situ, with the freeze-drying process automated for easy operation.
2. The board layer circulates a medium for temperature control, with a temperature difference ≤ 1°C, ensuring more even cooling and heating effects.
3. Touchscreen operation, PLC control system, real-time monitoring of equipment operation.
4. Connectable to computers, remotely controllable, and capable of storing lyophilization curves.
5. Integrated design for easy transportation and installation, saving space.
6. Features include CIP in-place cleaning, SIP in-place sterilization, hydraulic stopper system, and more.
Equipment Application Fields
1. Pharmaceutical Industry: The freeze-drying technique can be utilized for the dehydration and preservation of dry and paste-like traditional and Western medicines, vaccines, enzymes, antibiotics, hormones, etc.
2. Food Industry: Vacuum freeze-drying technology is primarily used in the food industry for drying coffee, leafy vegetables, fruit juices, strawberries, whole shrimps, meats, specialty vegetables, etc. It preserves the color, aroma, flavor, shape, and nutritional value of the food, making it easy for long-term storage and transportation. It is highly suitable for the production of convenient and nutritious food products.
3 Nutritional Health Products: The vacuum freeze-drying technique is also suitable for drying royal jelly, pearl powder, ginseng, fish meal, ant powder, snake powder, and more. It can preserve their nutritional and active ingredients for long periods.
Ensure the naturalness of the nutritional supplements.
4. Biological Research: The use of vacuum freeze-drying technology allows for long-term preservation of bacteria, arteries, bones, skin, corneas, and nerve tissues, as well as various organs. Upon use, water can be replenished to regenerate, maintaining their integrity.
Its biochemical and physical properties.
5. Other applications, such as in the production of aerospace thermal insulation ceramics, wood and silk artifacts in archaeology, preservation of products, specimen making, and preparation of special materials, yield unique effects.
Principle of Freeze-Drying
Drying is one method of preserving substances from spoilage and deterioration. There are many ways to dry, such as sun drying, boiling dry, air drying, spray drying, and vacuum drying, etc. However, these drying methods are all based onPerform at temperatures of 0℃ or higher. The dried product is generally reduced in volume, hardened in texture, with some substances oxidized, and most volatile components lost. Some thermosensitive substances, like proteins, may denature. Microorganisms lose biological activity, and the dried substance is less soluble in water. Consequently, there are significant differences in the properties of the product after drying compared to before. Unlike the above dry-frying methods, the freeze-drying process involves drying the product at temperatures below 0℃, i.e., while the product is frozen, until the later stage when the product is heated to above 0℃ to further reduce the residual moisture content, but usually not exceeding 50℃. Freeze-drying involves pre-freezing a substance containing a large amount of water into a solid, then, under vacuum conditions, allowing water vapor to sublime directly, leaving the substance itself in the ice matrix formed during freezing, resulting in a dry product that is疏松, porous, and maintains its volume. To decrease the product's temperature and slow the sublimation rate, it is necessary to apply appropriate heating. The entire drying process is conducted at lower temperatures.
Advantages of Freeze-Drying
1. Freeze-drying is conducted at low temperatures, making it particularly suitable for many thermosensitive substances, such as proteins and microorganisms, which do not denature or lose their biological activity. As a result, it is widely used in the pharmaceutical industry.
2. During low-temperature dry roasting, there is minimal loss of volatile components in the material, making it suitable for drying certain chemical products, pharmaceuticals, and foodstuffs.
3. During the freeze-drying process, microbial growth and enzyme activity are halted, thus preserving the original properties.
4. Due to drying in a frozen state, the volume remains almost unchanged, maintaining the original structure without any concentration.
5. The dried material is loose and porous, resembling a sponge. Upon addition of water, it dissolves quickly and completely, almost immediately reverting to its original properties.
6. Due to the drying process occurring under vacuum with limited oxygen, some materials prone to oxidation are protected.
7. Drying can remove over 95% of the moisture, allowing the product to be stored long-term post-drying without spoilage.
Thus, freeze-drying is currently widely applied in the pharmaceutical industry, food industry, scientific research, and other sectors.
