Mixing low-density powders with liquids can be challenging using a vacuum degassing machine, which may lead to dust issues and air exposure. Minimizing the introduction of air is crucial, as trapped air bubbles are difficult to remove. This can directly cause the opacity of translucent gels and lead to problems with product packaging being filled by volume rather than weight. Typically, longer processing times are required to ensure even dispersion.

When using a vacuum degassing machine, it can affect the occurrence of stratification, especially when there is a significant viscosity difference between the phases. This often leads to longer mixing times, poor consistency, and variations between batches.